We Are Spark

At Spark Therapeutics, we’re working to unlock the power of gene therapy to accelerate healthcare transformation.

Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases.

Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our vision to create a world where no life is limited by disease. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.

Our mission

We unlock the power of gene therapy to accelerate healthcare transformation.

Our vision

A world where no life is limited by disease.

Meet the Spark corporate management team

About Compliance and Ethics

Industry recognitions

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  • Philadelphia Business Journal Best Places to Work 2019