Partner With Us

Working with us means collaborating with peers who share a desire to change people’s lives and improve long-term health through our passion for innovative science and pioneering technology.

If you have an opportunity for collaboration or an interesting technology, or if you have an asset in one of our areas of interest, we would like to hear from you.

Spark’s Capabilities

We advance groundbreaking gene therapies using our unique end-to-end capabilities, including discovery research, manufacturing, product development and regulatory advancement, and U.S. commercialization.

Discovery Research

Advancing research programs against targets in the retina, liver, and central nervous system

Leveraging cutting-edge proprietary adeno-associated viral (AAV) vector platform


2 in-house manufacturing suites – capable of adherent and suspension manufacturing processes – used for both clinical and commercial manufacturing

Robust networks of 10 different CMOs

Product Development / Regulatory

Deep experience collaborating with investigators and regulators to develop rigorous and novel endpoints

Responsible for numerous development milestones in gene therapy

U.S. Commercial

Launched first FDA-approved gene therapy for a genetic disease

Established multi-faceted commercial capabilities to meet demands of this new and innovative therapeutic approach to healthcare

First of their kind diagnostic support, patient access programs and payer models

Why We Make a Good Partner

Spark is committed to collaborating within our teams and across companies towards the goal of bringing treatments to patients and their families living with genetic diseases. In our partnerships, we bring our top experts and the barrier-breaking spirit that defines our company. We value the expertise that our partners bring to the table, and we work to create lasting relationships. We truly believe that when we all work together, we can realize the full potential of our end goals.

Spark’s four-step partnering process:

1. Identify
the areas of

2. Search
for latest

3. Engage
with potential

4. Build
a lasting

Recent Deals and Partnerships

Spark has engaged in multiple partnerships that have successfully accelerated drug discovery and development. Our collaborations range from research to technologies to early-stage assets, and we work with each partner to bring different expertise and complementary capabilities. Learn more about our recent deals and partnerships.

What makes us different?
We are passionate about advancing science with you

We are a pioneer in gene therapy across a variety of disease areas

Working with us means working respectfully with our partners

Our approach to partnering is open and flexible