We Are Spark

At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases.

Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases. Our initial focus is on treating orphan diseases.

Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our goal to break down barriers for people and families affected by genetic diseases. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.

Our mission

Challenge the inevitability of genetic disease by discovering, developing and delivering treatments in ways unimaginable – until now.

Our vision

A world where no life is limited by genetic disease.

Meet the Spark corporate management team

About Compliance and Ethics

Industry recognitions

  • Philadelphia Business Journal Best Places to Work 2019

Our commitment to the community

While the investigational gene therapies we are discovering and developing are potentially ground breaking, the enormity of our goal keeps us humble and focused on the lives we hope to change. Patients are our guiding force, and we are honored to be part of their community.

Community to Spark has many meanings:

Sparking A Change in Our Community Through STEM

Team Spark Champions the Patient at Local Walks

Spark Sponsors Believe Limited’s First-Ever Science Fair for the Hemophilia Community at 2019 National Hemophilia Foundation’s Bleeding Disorders Conference

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